The dependence of function renormalization group equation on regulators is investigated. A parameter is introduced to quantify the suppression of regulators. Functional renormalization group equations will become regulator-independent if the newly introduced parameter is sent to infinity in the end of calculation. One-loop renormalization flow equations of QCD are derived. The novelty is that both the coupling running equation and the mass running equation are mass-dependent. By using these equations together with contributions from two-loop of assumed form, chiral symmetry breaking is discussed. And the conformal window is discussed in the language of renormalization flow.