Breast Cancer Stem Cells: Eradication by Differentiation Therapy?
langtu 添加于 2009-10-27 12:29
| 751 次阅读 | 0 个评论
作 者
Beug H
摘 要
During metastasis, migrating breast cancer stem cells undergo a loss of polarity leading to an epithelial-to-mesenchymal transition (EMT). Gupta et al. (2009) use this attribute of cancer stem cells to develop a high-throughput screen, which successfully identifes small molecules that specifcally inhibit cancer stem cell proliferation through the induction of differentiation. -
详细资料
- 文献种类:期刊
- 期刊名称: Cell
- 期刊缩写: Cell
- 期卷页: 2009年 第138卷 第4期 623-625页
- ISBN: 0092-8674
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