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RANK, RANKL and osteoprotegerin in bone biology and disease

wangjianwu 添加于 2009-11-16 22:06 | 1370 次阅读 | 0 个评论

作者
Wright HL, McCarthy HS, Middleton J, Marshall MJ
摘要
Upon the discovery of RANK, RANKL and OPG in the late 1990s, their importance in the maintenance of the skeletal structure and their dramatic role in bone disease were largely unexpected. In recent years the understanding of these proteins, in particular their regulation, has greatly increased. This review aims to bring the interested reader up to date with the latest news and views on the mechanisms controlling bone resorption in normal and pathological conditions.
详细资料
- 文献种类:期刊
- 期刊名称: Current Reviews in Musculoskeletal Medicine
- 期刊缩写: Curr Rev Musculoskelet Med
- 期卷页: 2009年第2卷第1期 56-64页
- 地址: ISTM, Medical School, Keele University at the Leopold Muller Arthritis Research Centre, RJAH Orthopaedic Hospital, Oswestry, Shropshire, SY10 7AG, UK, HelenL.smith@rjah.nhs.uk
- ISBN: 1935-973X
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