Fundamental Concepts in Biophysics(Volume 1) by Thomas Jue
Fundamental Concepts in Biophysics, the authors lay down afoundation for biophysics study. Rajiv Singh opens the book by pointingto the central importance of "Mathematical Methods in Biophysics."William Fink follows with a discussion on "Quantum Mechanics Basic toBiophysical Methods." Together, these two chapters establish some ofthe principles of mathematical physics underlying many biophysicstechniques. Because computer modeling forms an intricate part ofbiophysics research, Subhadip Raychaudhuri and colleagues introduce theuse of computer modeling in "Computational Modeling of Receptor–LigandBind-ing and Cellular Signaling Processes." Yin Yeh and coworkers bringto the reader’s attention the physical basis underlying the common useof fluorescence spectroscopy in biomedical re-search in their chapter"Fluorescence Spectroscopy." Electrophysiologists have also appliedbiophysics techniques in the study of membrane proteins, and Tsung-YuChen et al. explore stochastic processes of ion transport in their"Electrophysiological Measurements of Membrane Proteins." MichaelSaxton takes up a key biophysics question about particle distributionand behavior in systems with spatial or temporal inhomogeneity in hischapter "Single-Particle Tracking." Finally, in "NMR Measurement ofBiomolecule Diffusion," Thomas Jue explains how magnetic resonancetechniques can map biomolecule diffusion in the cell to a theory ofrespiratory control .
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